d angpt2 protein expression (Human Protein Atlas)
Structured Review

D Angpt2 Protein Expression, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/d angpt2 protein expression/product/Human Protein Atlas
Average 86 stars, based on 1 article reviews
Images
1) Product Images from "Integrated pan-cancer and melanoma-specific analysis of angiopoietin-2: prognostic value, immune microenvironment modulation, and ceRNA network regulation"
Article Title: Integrated pan-cancer and melanoma-specific analysis of angiopoietin-2: prognostic value, immune microenvironment modulation, and ceRNA network regulation
Journal: Discover Oncology
doi: 10.1007/s12672-025-03448-5
Figure Legend Snippet: Genetic alteration analysis of ANGPT2. A Genetic alterations of ANGPT2 across various cancers, showing a 4% alteration rate in pan-cancer samples. B Specific alteration sites within the ANGPT2 protein structure. C Frequency and types of ANGPT2 genetic alterations observed across different cancer types. D Correlation between ANGPT2 mRNA expression and genetic alterations across various cancers
Techniques Used: Expressing
Figure Legend Snippet: Expression of ANGPT2 in pan-cancer. A ANGPT2 mRNA expression levels in tumor versus normal tissues from the TIMER2.0 database. B ANGPT2 mRNA expression comparison between tumor and normal tissues from the combined TCGA and GTEx datasets. C Expression levels of ANGPT2 in tumors compared to paired adjacent normal tissues from the TCGA dataset. D ANGPT2 protein expression in tumor and normal tissues, based on data from the Human Protein Atlas (HPA). (ns: not significant, P ≥ 0.05; * P < 0.05; ** P < 0.01; *** P < 0.001)
Techniques Used: Expressing, Comparison
Figure Legend Snippet: Correlation of ANGPT2 with Pan-Cancer Prognosis and Diagnosis and Functional Enrichment Analysis of Related Genes. A Forest plot showing the association between ANGPT2 expression and overall survival in pan-cancer analysis ( P < 0.05). B Kaplan-Meier survival curves displaying the relationship between ANGPT2 expression and disease-specific survival (DSS) in cancers such as ACC, ESCA, KICH, LGG, LIHC, PAAD, SKCM, STAD, and UCS. C ROC curve analysis demonstrating the diagnostic value of ANGPT2 in cancers like ACC, ESCA, KICH, LGG, LIHC, PAAD, SKCM, STAD, and UCS. D Gene Ontology (GO) enrichment analysis of biological processes (BP), cellular components (CC), and molecular functions (MF) of the top 100 ANGPT2-related genes in tumors with high ANGPT2 expression. E KEGG pathway analysis of the top 100 ANGPT2-related genes in tumors with high ANGPT2 expression, showing involvement in key cancer-related pathways
Techniques Used: Biomarker Discovery, Functional Assay, Expressing, Diagnostic Assay
Figure Legend Snippet: ANGPT2 expression and immune infiltration analysis. A Correlation between ANGPT2 expression and immune cell infiltration across pan-cancer samples. B Association between ANGPT2 mRNA expression and ESTIMATE scores in SKCM, indicating the tumor microenvironment composition. C Relationship between ANGPT2 mRNA expression and stromal scores in SKCM. D Comparison of immune cell infiltration between high and low ANGPT2 expression groups in SKCM
Techniques Used: Expressing, Comparison
Figure Legend Snippet: lncRNA-miRNA-ANGPT2 network construction in SKCM. A Venn diagram showing predicted ANGPT2-targeting miRNAs from miRDB, miRWalk, and Starbase 2.0 ENCORI databases. B Correlation analysis between ANGPT2 expression and miRNAs, including hsa-miR-205-5p, hsa-miR-514b-5p, hsa-miR-3121-3p, hsa-miR-3163, and hsa-miR-5000-3p. C Relationships between the identified miRNAs and their target lncRNAs. D A ceRNA regulatory network involving lncRNAs, miRNAs, and ANGPT2 was constructed for SKCM
Techniques Used: Expressing, Construct